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聚合物胶束作为药物载体及其在肿瘤靶向方面的研究进展

吴韫韬,  张依依

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文章导航 > 药学实践与服务  > 2013 >  31(2): 86-89,115
吴韫韬, 张依依. 聚合物胶束作为药物载体及其在肿瘤靶向方面的研究进展[J]. 药学实践与服务, 2013, 31(2): 86-89,115. doi: 10.3969/j.issn.1006-0111.2013.02.002
引用本文: 吴韫韬, 张依依. 聚合物胶束作为药物载体及其在肿瘤靶向方面的研究进展[J]. 药学实践与服务, 2013, 31(2): 86-89,115. doi: 10.3969/j.issn.1006-0111.2013.02.002
shu
WU Yun-tao, ZHANG Yi-yi. Advances in polymeric micelles for drug delivery and tumor targeting[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 86-89,115. doi: 10.3969/j.issn.1006-0111.2013.02.002
Citation: WU Yun-tao, ZHANG Yi-yi. Advances in polymeric micelles for drug delivery and tumor targeting[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 86-89,115. doi: 10.3969/j.issn.1006-0111.2013.02.002
shu

聚合物胶束作为药物载体及其在肿瘤靶向方面的研究进展

doi: 10.3969/j.issn.1006-0111.2013.02.002

  • 上海交通大学医学院附属新华医院, 上海 200092

Advances in polymeric micelles for drug delivery and tumor targeting

  • Xinhua Hospital, Shanghai Jiaotong University, Shanghai 200092, China

  • 摘要: 聚合物胶束具有粒径小、稳定性高、滞留时间长、良好的生物相容性等特点,这些优良性质使得聚合物胶束作为药物载体具有许多独特的优势。近年来,涌现了许多围绕聚合物胶束设计肿瘤靶向给药系统的报道,包括利用肿瘤的病理学性质,设计被动靶向给药系统和对聚合物胶束进行表面修饰,设计主动靶向给药系统。本文主要综述了聚合物胶束作为肿瘤靶向药物载体的研究进展。
    Abstract: Some unique inherent properties of polymeric micelles, including small particle size, high stability, long residence time, and good biocompatibility allowed polymeric micelles to be used as drug carriers. In recent years, increasing reports about the polymer micelles had been designed for tumor targeted drug delivery systems, including passive targeted drug delivery using tumor pathological nature and active targeting drug delivery using surface modification of polymer micelles. The research progress of polymeric micelles used as tumor targeted drug carriers were reviewed in this paper.
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  • 收稿日期:  2012-05-05
  • 修回日期:  2012-10-09

聚合物胶束作为药物载体及其在肿瘤靶向方面的研究进展

doi: 10.3969/j.issn.1006-0111.2013.02.002
  • 上海交通大学医学院附属新华医院, 上海 200092
  • 收稿日期: 2012-05-05
  • 修回日期: 2012-10-09

摘要: 聚合物胶束具有粒径小、稳定性高、滞留时间长、良好的生物相容性等特点,这些优良性质使得聚合物胶束作为药物载体具有许多独特的优势。近年来,涌现了许多围绕聚合物胶束设计肿瘤靶向给药系统的报道,包括利用肿瘤的病理学性质,设计被动靶向给药系统和对聚合物胶束进行表面修饰,设计主动靶向给药系统。本文主要综述了聚合物胶束作为肿瘤靶向药物载体的研究进展。

English Abstract

吴韫韬, 张依依. 聚合物胶束作为药物载体及其在肿瘤靶向方面的研究进展[J]. 药学实践与服务, 2013, 31(2): 86-89,115. doi: 10.3969/j.issn.1006-0111.2013.02.002
引用本文: 吴韫韬, 张依依. 聚合物胶束作为药物载体及其在肿瘤靶向方面的研究进展[J]. 药学实践与服务, 2013, 31(2): 86-89,115. doi: 10.3969/j.issn.1006-0111.2013.02.002
shu
WU Yun-tao, ZHANG Yi-yi. Advances in polymeric micelles for drug delivery and tumor targeting[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 86-89,115. doi: 10.3969/j.issn.1006-0111.2013.02.002
Citation: WU Yun-tao, ZHANG Yi-yi. Advances in polymeric micelles for drug delivery and tumor targeting[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 86-89,115. doi: 10.3969/j.issn.1006-0111.2013.02.002
shu

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