Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 28 Issue 2
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(2): 105-106,121

ZHANG Guo-qing, WANG Ke-bing. Anticancer and phytochemical properties of alkaloids from Caragana microphylla[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(2): 105-106,121.
Citation: ZHANG Guo-qing, WANG Ke-bing. Anticancer and phytochemical properties of alkaloids from Caragana microphylla[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(2): 105-106,121.
shu

Anticancer and phytochemical properties of alkaloids from Caragana microphylla

  • The 169th hospital of PLA,Hengyang 421002,China

  • Received Date: 2009-10-21
  • Rev Recd Date: 2010-02-19
  • Objective To identify the composition of the total alkaloids of the seeds of Caragana microphylla,a native plant from the North west of China which is used in traditional Mongolian medicines. Methods The alkaloids was separated and identified by chromatographic Methods and spectral analysis.The anticancer activities of the total alkaloids and the isolated protoberberine alkaloids were tested respectively on Saos-2,A375 and Hela cell lines. Results Five protoberberine alkaloids including dehydrothalictrifoline,coptisine,epiberberine,dehydroapocavidine and corysamine were isolated.The totel alkaloids and the 5 alkaloids were found to be very effective against three tumor cell lines. Conclusion s The 5 protoberberine alkaloids were isolated for the first time from Caragana genus.Caragana microphylla seed extracts may play a role as an hopefulanticancer therapeutic agent.
  • 加载中
通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2532) PDF downloads(550) Cited by()

Related
Proportional views

Anticancer and phytochemical properties of alkaloids from Caragana microphylla

  • The 169th hospital of PLA,Hengyang 421002,China
  • Received Date: 2009-10-21
  • Rev Recd Date: 2010-02-19

Abstract: Objective To identify the composition of the total alkaloids of the seeds of Caragana microphylla,a native plant from the North west of China which is used in traditional Mongolian medicines. Methods The alkaloids was separated and identified by chromatographic Methods and spectral analysis.The anticancer activities of the total alkaloids and the isolated protoberberine alkaloids were tested respectively on Saos-2,A375 and Hela cell lines. Results Five protoberberine alkaloids including dehydrothalictrifoline,coptisine,epiberberine,dehydroapocavidine and corysamine were isolated.The totel alkaloids and the 5 alkaloids were found to be very effective against three tumor cell lines. Conclusion s The 5 protoberberine alkaloids were isolated for the first time from Caragana genus.Caragana microphylla seed extracts may play a role as an hopefulanticancer therapeutic agent.

ZHANG Guo-qing, WANG Ke-bing. Anticancer and phytochemical properties of alkaloids from Caragana microphylla[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(2): 105-106,121.
Citation: ZHANG Guo-qing, WANG Ke-bing. Anticancer and phytochemical properties of alkaloids from Caragana microphylla[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(2): 105-106,121.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: [email protected]

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return