2012 Vol. 30, No. 4
Display Method:
2012, 30(4): 241-247.
Abstract:
There was a research focus for the prevention of diseases by way of binding to DNA using small molecules.The discovery of structures of G-quadruplex and its fimction related to cancer thtough modern molecular biology techniques provided a big chance ...
There was a research focus for the prevention of diseases by way of binding to DNA using small molecules.The discovery of structures of G-quadruplex and its fimction related to cancer thtough modern molecular biology techniques provided a big chance ...
2012, 30(4): 248-253,295.
Abstract:
Objective To introduce the progress on synthesis and biological activity of 2-pyridyl ketone derivatives.Methods The information described in literature both at home and abroad was reviewed.Results and Conclusion Basedon the results of existedresearc...
Objective To introduce the progress on synthesis and biological activity of 2-pyridyl ketone derivatives.Methods The information described in literature both at home and abroad was reviewed.Results and Conclusion Basedon the results of existedresearc...
2012, 30(4): 254-257,301.
Abstract:
Nanostructured lipid carrier,which could enhance the bioavailability of poorly soluble drugs,was a kind of promisingoral delivery systems for insoluble drugs.The preparation,characterization, drug release in vitro and the mechanism of NLC for enhanci...
Nanostructured lipid carrier,which could enhance the bioavailability of poorly soluble drugs,was a kind of promisingoral delivery systems for insoluble drugs.The preparation,characterization, drug release in vitro and the mechanism of NLC for enhanci...
2012, 30(4): 258-261,312.
Abstract:
Catharanthus roseus (L.) G. Don contained more than 100 known indole alkaloids, some of which had anti-cancer, lowering blood pressure and other biological activity. Catharanthus roseus had a high medicinal value, but the content of alkaloids was ver...
Catharanthus roseus (L.) G. Don contained more than 100 known indole alkaloids, some of which had anti-cancer, lowering blood pressure and other biological activity. Catharanthus roseus had a high medicinal value, but the content of alkaloids was ver...
2012, 30(4): 262-265.
Abstract:
Mesoporous molecular sieves was a new material in the aperture between the microporous and macroporous, which had significant hemostatic,anti-microbial effect. Mesoporous materials had been widely employed as carriers for controlled drug release and ...
Mesoporous molecular sieves was a new material in the aperture between the microporous and macroporous, which had significant hemostatic,anti-microbial effect. Mesoporous materials had been widely employed as carriers for controlled drug release and ...
2012, 30(4): 266-268,298.
Abstract:
Salvia was a traditional Chinese medicine, which was widely used for cardiovascular treatment. The water-soluble components of Salvia was Danshensu, which had become one of the research hotspots. In recent years,the pharmacological research of danshe...
Salvia was a traditional Chinese medicine, which was widely used for cardiovascular treatment. The water-soluble components of Salvia was Danshensu, which had become one of the research hotspots. In recent years,the pharmacological research of danshe...
2012, 30(4): 269-274,278.
Abstract:
Objective To find out the best prescription method for Yantongping transdermal ointments through orthogonal design and research on the effect of promoting blood circulation. Methods With 60 minutes in vitro cumulative penetration rate, using L9(34) o...
Objective To find out the best prescription method for Yantongping transdermal ointments through orthogonal design and research on the effect of promoting blood circulation. Methods With 60 minutes in vitro cumulative penetration rate, using L9(34) o...
2012, 30(4): 275-278.
Abstract:
Objective To investigate the chemical constituents from leaves of Rosa Laevigata Michx.Methods The chemical constituents were isolated and purifieated by silica gel column chromatography,Sephadex LH-20 and semi-preparative RP-HPLC. Their structures w...
Objective To investigate the chemical constituents from leaves of Rosa Laevigata Michx.Methods The chemical constituents were isolated and purifieated by silica gel column chromatography,Sephadex LH-20 and semi-preparative RP-HPLC. Their structures w...
2012, 30(4): 279-282,286.
Abstract:
Objective To analyze the the compositions of volatile oil from Artemisia argyi Levi.et Vant extracted by three different methods by GC-MS.Methods The volatile oil from Artemisia argyi Levi.et Vant were extracted by Steam distillation,Hexane reflux ex...
Objective To analyze the the compositions of volatile oil from Artemisia argyi Levi.et Vant extracted by three different methods by GC-MS.Methods The volatile oil from Artemisia argyi Levi.et Vant were extracted by Steam distillation,Hexane reflux ex...
2012, 30(4): 283-286.
Abstract:
objective To develop the population pharmacokinetics model of sibutramine (SIB) in Chinese healthy volunteers.Methods Twenty male healthy volunteers were enrolled into the study.13 blood sampling were drawn after administration of 10 mg SIB within 24...
objective To develop the population pharmacokinetics model of sibutramine (SIB) in Chinese healthy volunteers.Methods Twenty male healthy volunteers were enrolled into the study.13 blood sampling were drawn after administration of 10 mg SIB within 24...
2012, 30(4): 287-288,304.
Abstract:
Objective To improve the preparation process of tamibarotene.Methods 1,2,3,4-tetrahydro-1,1,4,4-tetram-ethyl-6-acelylaminonaphthalimide was prepared from 2,5-dimethyl-2,5-hexanediol by chloridized and Friedel-Craft reaction with acetauilide,which was...
Objective To improve the preparation process of tamibarotene.Methods 1,2,3,4-tetrahydro-1,1,4,4-tetram-ethyl-6-acelylaminonaphthalimide was prepared from 2,5-dimethyl-2,5-hexanediol by chloridized and Friedel-Craft reaction with acetauilide,which was...
2012, 30(4): 289-290,309.
Abstract:
Objective To establish the HPLC method for determination of baicalin in Bianyan oral solution,and evaluate the transfer rate in process of production.Methods The Agilent Zorbax Eclipse XDB-C18 (4.6 mm×150 mm,5μm) was used,the mobile phase consisted o...
Objective To establish the HPLC method for determination of baicalin in Bianyan oral solution,and evaluate the transfer rate in process of production.Methods The Agilent Zorbax Eclipse XDB-C18 (4.6 mm×150 mm,5μm) was used,the mobile phase consisted o...
2012, 30(4): 291-292,319.
Abstract:
Objective To confirm the effect of interval usage of furosemide and torasemide in treatment of chronic heart failure (CHF).Methods By simple randomization,the patients were divided into the observe group (interval usage of furosemide and torasemide) ...
Objective To confirm the effect of interval usage of furosemide and torasemide in treatment of chronic heart failure (CHF).Methods By simple randomization,the patients were divided into the observe group (interval usage of furosemide and torasemide) ...
2012, 30(4): 293-295.
Abstract:
Objective To assess the efficacy of recombinant human growth hormone (rhGH) therapy in late puberty children with idiopathic short stature. Methods 11 children in late puberty with idiopathic short stature (ISS) were divided into 2 groups according t...
Objective To assess the efficacy of recombinant human growth hormone (rhGH) therapy in late puberty children with idiopathic short stature. Methods 11 children in late puberty with idiopathic short stature (ISS) were divided into 2 groups according t...
2012, 30(4): 296-298.
Abstract:
Objective To observe the effect and safety of exenatide combined pioglitazone on type 2 diabetes.Methods 68 patients with type 2 diabetes who took pioglitazone for some time and still could not control the blood glucose effectively.In that case,every...
Objective To observe the effect and safety of exenatide combined pioglitazone on type 2 diabetes.Methods 68 patients with type 2 diabetes who took pioglitazone for some time and still could not control the blood glucose effectively.In that case,every...
2012, 30(4): 299-301.
Abstract:
Objective To explore the effect of valsartan on patients with hypertension and non-alcoholic fatty liver disease (NAFLD),Methods A total of 148 patients suffered hypertension and NAFLD were included in the study. Patients were divided into the observ...
Objective To explore the effect of valsartan on patients with hypertension and non-alcoholic fatty liver disease (NAFLD),Methods A total of 148 patients suffered hypertension and NAFLD were included in the study. Patients were divided into the observ...
2012, 30(4): 302-304.
Abstract:
Objective To investigate the effects of Fe“on the stability of ornidazole and sodium chloride injection,and ensure the safety in elinical utility. Methods Two kinds of ornidazole and sodium chloride injection which contain no Fe3+ and trace Fe3+ were...
Objective To investigate the effects of Fe“on the stability of ornidazole and sodium chloride injection,and ensure the safety in elinical utility. Methods Two kinds of ornidazole and sodium chloride injection which contain no Fe3+ and trace Fe3+ were...
2012, 30(4): 305-306,315.
Abstract:
Objective To establish a method to determine GSH and GSSG by HPLC. Method The analytical column was Hypersil C18. The mobile phase consisted of 25m mol/L KH2PO4 (pH2.5):tetrahydrofuran (100:1). The flow rate was 1.0 ml/min. Column temperature was 30 ...
Objective To establish a method to determine GSH and GSSG by HPLC. Method The analytical column was Hypersil C18. The mobile phase consisted of 25m mol/L KH2PO4 (pH2.5):tetrahydrofuran (100:1). The flow rate was 1.0 ml/min. Column temperature was 30 ...
2012, 30(4): 307-309.
Abstract:
Objective To establish a high performance liquid chromatography method for the determination of buddleoside in Zhikuoyangyin granules. Methods The HPLC method was performed on a DIKMA Platisil ODS column (250 mm×4.6 mm,5 μm) with the mobile phase con...
Objective To establish a high performance liquid chromatography method for the determination of buddleoside in Zhikuoyangyin granules. Methods The HPLC method was performed on a DIKMA Platisil ODS column (250 mm×4.6 mm,5 μm) with the mobile phase con...
2012, 30(4): 310-312.
Abstract:
The characteristics of experiment in pharmaceutical specialties and the current situation that sonic experimental teaching courses were fragmented in pharmaceutical specialties were analyzed in this article.According to the general rules of the drug ...
The characteristics of experiment in pharmaceutical specialties and the current situation that sonic experimental teaching courses were fragmented in pharmaceutical specialties were analyzed in this article.According to the general rules of the drug ...
2012, 30(4): 313-315.
Abstract:
Objective To build up the teaching tacties of research in experiment course for pharmaceutical specialties,which could promote the ability of practicing and innovation,and cultivate the talents combined with fundamental research,new drug development ...
Objective To build up the teaching tacties of research in experiment course for pharmaceutical specialties,which could promote the ability of practicing and innovation,and cultivate the talents combined with fundamental research,new drug development ...
2012, 30(4): 316-319.
Abstract:
Pharmaceutical Botany was a professional basic course of pharmacy major. Teaching material was the important part of teaching affair. The edit task of the projected teaching material in four editions had been taken up by us. The 5 th projected teachi...
Pharmaceutical Botany was a professional basic course of pharmacy major. Teaching material was the important part of teaching affair. The edit task of the projected teaching material in four editions had been taken up by us. The 5 th projected teachi...
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