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2010 Vol. 28, No. 1

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Display Method:
2010, 28(1): 1-2,47.
Abstract(3001) PDF (759KB)(1536)
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2010, 28(1): 3-6,10.
Abstract(2204) PDF (1155KB)(1757)
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Experimental design for the prediction of drug validity duration and the investigation of influences on drug stability
CHEN Jian-ming, DENG Li, WANG Xiu-xin, HUANG Shou, GAO Bao-an, ZHONG Yan-qiang, LU Ying, DING Xue-ying
2010, 28(1): 7-10.
Abstract(3008) PDF (629KB)(1204)
Abstract:
Objective To investigate the feasibility of temozolomide replacement of vitamin C and penicillin to evaluate the drug stability for students,experiment;to establish the experimental method to predict the validity duration of temozolomide at room tem...
Stability studies of lysozyme for preformulation
ZHOU Gui-chen, LIU Qing-feng, LU Ying, ZHONG Yan-qiang
2010, 28(1): 11-13,44.
Abstract(2902) PDF (1000KB)(995)
Abstract:
Objective To investigate the influence of pH value,temperature,protectant and organic solvent on the physical stability and biological activity of lysozyme. Methods The concentration of lysozyme was determined by HPLC and the biological activity of...
Determination of cinnamaldehyde and glycyrrhizic acid in Qiwei Putao power by HPLC
LIU Gang, TAN Sheng-jian, XIE Ya-jun, LIU Yan, ZHANG Hua, JIANG Ren
2010, 28(1): 14-16.
Abstract(2625) PDF (173KB)(628)
Abstract:
Objective To establish an HPLC quantitative method for the determination of cinnamaldehyde and glycyrrhizic acid in Qiwei Putao power simultaneously. Methods The chromatographic conditions include column C18(Agilent ZORBAX Eclipse SB-C18,4.6@150 mm...
GC-MS/MS analysis of the low polarity components from the root of Arnebia euchroma
LIU Hong, CHEN Hai-sheng, GENG Dong-sheng, JIN Yong-shen, YANG Xian-nan
2010, 28(1): 17-18,59.
Abstract(2560) PDF (493KB)(960)
Abstract:
Objective To investigate the low polarity components from the root of Arnebia euchroma. Methods The EtOH extracts of the root of Arnebia euchroma was extracted with petroleum ether.Part of the petroleum ether extraction was acetylated.The component...
Experimental study of therapeutic effects on osteoarthritis with sodium hyaluronate of different molecular weight
LU Ming-zhu, LU Wen-quan, YI Jia, CAI Guo-jun
2010, 28(1): 19-22.
Abstract(2505) PDF (747KB)(827)
Abstract:
Objective To study the therapeutic effects of sodium hyaluronate injection of different molecular weight(MW: 800~1500 kDa vs.1500~2500 kDa) on osteoarthritis. Methods Two kinds of osteoarthritis models were induced in rabbit’s knee joints: long-ter...
Effect of development of conditioned place preference on behavioral sensitization induced by morphine in mice
SUN Ting, ZOU Ying-xin, ZHENG Jie-min, HUANG Mao, ZHANG Xiao-dong
2010, 28(1): 23-24,72.
Abstract(2629) PDF (526KB)(483)
Abstract:
Objective To observe the effect of development of conditioned place preference on behavioral sensitization induced by morphine in mice. Methods Male mice were used as subjects.Total range of motion after treated with morphine and haloperidol were e...
Etoposide induces apoptosis via ubiquitin-proteasome pathway in HL-60 leukemia cells
YE Qi, WANG Jing, GUO Xue-qing, CHEN Chong-hong, ZHANG Jun-ping
2010, 28(1): 25-28,69.
Abstract(3050) PDF (516KB)(803)
Abstract:
Objective To investigate the molecular mechanisms of Topoisomerase II inhibitor etopside(induced apoptosis on human leukemia HL-60 cells. Methods Cell growth and apoptosis were determined by MTT assay and flow cytometry.cDNA microarray was used to ...
Effect of MDR1C3435T genetic polymorphism on concentration/dose and efficacy of tacrolimus in patients with kidney transplantation
HOU Ming-ming, SONG Hong-tao, WANG Qing-hua, YANG Shun-liang, TAN Jian-ming
2010, 28(1): 29-31.
Abstract(2620) PDF (637KB)(669)
Abstract:
Objective To investigate the impact of MDR1C3435T genetic polymorphism on the concentration/dose(C/D) ratio,acute rejection and adverse effect of tacrolimus(FK506)in the renal patients after transplantation. Methods The MDR1C3435T genotype was dete...
Influence of two immunosuppression regimens on peripheral blood parameters and erythropoietin of kidney transplantation recipients
YANG Li-hong, LI Xiao-ong, Pan Xiao-dong, WANG Ming-shan, CHEN Bi-cheng, LIN Yong-tong
2010, 28(1): 32-33,72.
Abstract(2645) PDF (171KB)(564)
Abstract:
Objective To investigate the effect on peripheral blood parameters and erythropoietin(EPO) of renal transplantation patients with different treatment of new immunosuppressive agents. Methods According to different immunosuppressive regimens,recipie...
Preparation and quality control of danyi kangtai capsule
MIAO Li-cheng, WU Chao-lun, HAN Wei-jia, NIE Feng-wen, XU Yue
2010, 28(1): 34-35,39.
Abstract(2677) PDF (589KB)(438)
Abstract:
Objective To develop Danyi Kangtai capsule and establish of its quality control Methods . Methods The best prescription was determined,and the quality control was established through the identification,determination of content,etc.And the content ...
Study on gelation method of bacterial endotoxin test in goserelin acetate sustained-release depot
HU Yu-chi, YANG Yun-yun, ZHU Chun-yue, ZHOU Jian-ping
2010, 28(1): 36-39.
Abstract(3347) PDF (580KB)(841)
Abstract:
Objective To confirm the feasibility of gelation method of bacterial edotoxins tests for goserelin acetate sustained-release depot. Methods Acetonitrile were added to dissolve the sustained-release depot,the goserelin acetate will been precipitated...
Determination of sinomenine in Wuten Zhentong capsules by HPLC
QIU Cai-rong, LI Xin-tian, LIN Yu, CHEN Chong-shang
2010, 28(1): 40-42.
Abstract(3303) PDF (556KB)(308)
Abstract:
Objective To establish an HPLC method for determining the content of sinomenine in Wuten Zhentong capsule. Methods The sample was analyzed on a Shim-pack CLC-ODS-C18(150 mm×4.6 mm,5 μm) column using methanol-phosphate buffer(5 mmol/L sodium hydroge...
Quantitative analysis of baicalin in Qinlan nasal drops by RP-HPLC
CHEN Wei-zhong
2010, 28(1): 42-44.
Abstract(2177) PDF (262KB)(290)
Abstract:
Objective To develop RP-HPLC method for the determination of baicalin in Qinlan nasal drops. Methods The chromatographic analysis was performed on Gemini C18 110A(4.60 mm×250 mm,5 μm)column.The mobile phase was consisted of methanol-0.2% phosphoric...
Determination of lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC
WANG Shu-dong, PAN Jing, FANG Li, XIA Shu-hui, SONG Bing-sheng
2010, 28(1): 45-47.
Abstract(2928) PDF (215KB)(624)
Abstract:
Objective To establish a quantitative determination method for lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC. Methods The determination was carried out with a Hedera-ODS-3 C18 column(4.6 mm×250 mm,5 μm).The mobil...
Content determination of compound thymol liniment by GC
DAI You-qin, ZHUO Kai-hua
2010, 28(1): 48-49.
Abstract(2355) PDF (149KB)(474)
Abstract:
Objective To establish a method of GC for determinating the content of compound thymol liniment: camphor and thymol. Methods The determination was carried out on a DB-624 capillary column with sequential increase of temperature programming. Results...
Studies on the chemical constituents of Ainsliaea macrocephala
XU Xi-ke, LIU Run-hui, SHAN Lei, SU Juan, LI Hui-liang, SHEN Yun-heng
2010, 28(1): 50-51,54.
Abstract(3252) PDF (535KB)(842)
Abstract:
Objective To study the chemical constituents of Ainsliaea macrocephala(Franch). Methods The isolation and purification were carried out by extraction,silica gel and Sephadex LH-20 column chromatography.The compounds were identified on the basis of ...
2010, 28(1): 52-54.
Abstract(2135) PDF (336KB)(698)
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2010, 28(1): 55-57.
Abstract(1987) PDF (137KB)(287)
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2010, 28(1): 57-59.
Abstract(2122) PDF (451KB)(366)
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2010, 28(1): 60-62.
Abstract(1981) PDF (66KB)(446)
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2010, 28(1): 63-64.
Abstract(2101) PDF (336KB)(529)
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2010, 28(1): 65-67.
Abstract(2149) PDF (153KB)(546)
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2010, 28(1): 67-69.
Abstract(1957) PDF (168KB)(404)
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2010, 28(1): 70-72.
Abstract(2142) PDF (629KB)(699)
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2010, 28(1): 73-75.
Abstract(2054) PDF (650KB)(772)
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