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2005 Vol. 23, No. 5

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2005, (5): 257-262.
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2005, (5): 263-265.
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Safety pharmacology study of KNT009
JIANG Hua, LU Guo-cai, YUAN Bo-jun, LI Zhi-yuan, SHE Jia-hong
2005, (5): 266-269.
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Objective To study the effects of KNT009 on nervous, cardiovascular and respiratory system in animals. Methods Mice were randomly divided to receive single 160, 80, 40, and 0 mg/kg dose of KNT009 and 80 mg/kg dose of gatigloxacin respectively and the...
Research on preparation of aripiprazole
XU Jian-ming, WU Qiu-ye, SUN Qing-yan, ZHANG Jun, YU Shi-chong
2005, (5): 269-270.
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Objective To optimize the preparation procedure of aripiprazole. Methods 7-hydroxy-3,4-dihydro-2(1H)-quinolin-one was used as starting material and etherified with 1,4-dibromobutane, then alkylated with 1-(2,3-dichlorophenyl) piperazine to yield the ...
Study on the model of gastric mucosal precancerous lesion in rat
WANG Shao-ming, LIN Cai-jing, YANG Chun-bo, SHI Zuo-lin, ZHUANG Jie, RUAN Jun-shan
2005, (5): 271-272,281.
Abstract:
Objective To establish a practical and effective animal model in order to study gastric mucosal precancerous lesion (GPL) in rat. Methods Three group were classified in the experimental. Normal group:not to establish the model; Model group Ⅰ establis...
2005, (5): 273-273.
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2005, (5): 274-275.
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2005, (5): 275-278.
Abstract(1888) PDF (2593KB)(1236)
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2005, (5): 278-281.
Abstract(3334) PDF (2593KB)(1808)
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Analysis on usage of β-receptor blocking drugs
KUANG Yu-xia
2005, (5): 282-284.
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Objective To investigate the status and tendency of β-receptor antagonists usage, and offer scientific basis for reasonable usage of the drugs in clinic treatment. Methods The data of β-receptor antagonists usage in Wuhan Asia Heart Hospital during 2...
2005, (5): 284-285.
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2005, (5): 285-287.
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Dynamic analysis of non-steroidal anti-inflammatory drugs used in Second Affiliated Hospital of Jiaxing College during 2002~2004
ZHU Yong-ming, TU Li-biao
2005, (5): 288-291.
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Objective To predict the developing trend of non-steroidal anti-inflammatory drugs and offer the base for drug development and clinical application by analyzing the current use situation of these drugs. Methods The use amount of non-steroidal anti-in...
Analysis of applicational frequency of antimicrobial drugs in one hospital during 2003~2004
WANG Jing, ZHOU Ping, WEN Ming, WU Guang-tong
2005, (5): 291-294.
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Objective To investigate the application and trend of antimierobial drugs in our hospital in order to provide some references for medical staffs and related unites. Methods Taking DDD, DDDs, total expenditure(yuan) and daily cost as statistic index, ...
Determination astragaloside Ⅳ in Radix Astragali by HPLC-ELSD
JI Song-gang, LI Xiang, ZHU Dong-liang, ZHANG Guo-qing, WANC Bin, LOU Zi-Yang
2005, (5): 295-297.
Abstract:
Objective To determine astragaloside Ⅳ in Radix Astragali by HPLC-KLSD. Methods Radix Astragali was extracted with MeOH-NH3·H2O(v/v 9:1),the condition was confirmed and the validation of the method was also tested. The chromatogra phy condition was w...
Determination of content in aripirazole tablets by HPLC
CHENG Yirig, PU Cun-hai, WU Ai-lan, WANG Bo
2005, (5): 297-299.
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Objective To established a HPLC method for the determination of alipaizuo in its tablets. Method Alipaizuo can be separated on column with a mixture of 0.02% phosphoric acid(pH=3.0, adjusted with triethylamine) and acetonitrile (46:54) as mobile phas...
Application of agglutinative limulus test to monitor bacterial endotoxin in flucon-azole and glucose injection
HUANG Xun-ming
2005, (5): 300-301.
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Objective To establish a method of bacterial endotoxin test for fluconazole and glucose injection using limulus lysate a-gent. Methods The experiment was made according to bacterial endotoxin test in China Pharmacopeia 2000 (vol. Ⅱ). Results Fluconaz...
Observation on the stability on infusions mixed with norfloxacin by convolution spectrometry
GAO Jin-bo, ZHANG Yu-nan, HOU Wei, ZHAO Hai-zhen
2005, (5): 302-304.
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Objective To observe the chemical stabihty of seven common injections (5% glucose injection, 10% glucose injection, 5% glucose and sodium chloride injection, 10% glucose and sodium chloride injection, compound sodium chloride injection, 0.9% sodium c...
2005, (5): 304-306.
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Measurement of endotoxin in clindamycin hydrochloride injection by the kineticturbidimetric technique
YUAN Qing-Hua, SUN Shu-lian, RUI jing, HUA Xiao-dong
2005, (5): 306-308.
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Objective To Establish the kinetre-turbidimetrie techmque for practical quahly control on endotoxin content in elmda invcin hydrochloride mjection Methods The kmetie-turbidimetrie techmque and ehminated interfere factors approved by Chinese pharmacop...
Consideration on adapting pharmaceutical information work for pharmaceutical care practice
SUN Zhong-jin
2005, (5): 309-312.
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Objective Pharmaceutical care is a brand-new model that rises rapidly in the 1990s. It's in the stage of spreading and popularizing in our country. However, pharmaceutical information work is the center and foundation of all the pharmaceutical care w...
2005, (5): 312-314.
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2005, (5): 314-314.
Abstract(1918) PDF (860KB)(388)
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2005, (5): 315-315.
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2005, (5): 316-320.
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