1999 Vol. 17, No. 5
Display Method:
1999, (5): 279-281.
Abstract:
OBJECTIVE To study the effects of Gypenosides (GPs) on neoplasm growth, total number of splenic cells and NK cell activity. METHODS Antitumor experiment in mice was made and the total number of splen cells and NK cell activity were determined. RESULTS GPs could significantly inhibit the growth of Lewis lung cancer in mice. The inhibiting rates of tumor were (30.7±1.2)%,(51.5±2.5)% and (50.3±1.5)% (P<0.01) after ip GPs 10,20 and 40mg/kg,respectively. The total number of splenic cells and the NK cell activity of both PBL and splenic cells were elevated. CONCLUSION The antitumor effect of GPs is related to the elevated immunological function of tumor grafted mice.
OBJECTIVE To study the effects of Gypenosides (GPs) on neoplasm growth, total number of splenic cells and NK cell activity. METHODS Antitumor experiment in mice was made and the total number of splen cells and NK cell activity were determined. RESULTS GPs could significantly inhibit the growth of Lewis lung cancer in mice. The inhibiting rates of tumor were (30.7±1.2)%,(51.5±2.5)% and (50.3±1.5)% (P<0.01) after ip GPs 10,20 and 40mg/kg,respectively. The total number of splenic cells and the NK cell activity of both PBL and splenic cells were elevated. CONCLUSION The antitumor effect of GPs is related to the elevated immunological function of tumor grafted mice.
1999, (5): 288-290.
Abstract:
OBJECTIVE To avoid the irritation of oral ketoprofen in gastrointestinal tract,the ketoprofen gel was prepared. METHOD Ketoprofen was dispersed in gel base material after it had been dissolved in alcohol and had been neutralized with triethanolamine.And the method of determination,the irritation experiment and the research of absorption in vitro were studied. RESULTS The prescription of ketoprofen gel was rational.The preparation had low irritation and had high effect on percutaneous absorption in vitro. CONCLUSION The preparation could substitute for oral ketoprofen,and the clinic result should be more observed.
OBJECTIVE To avoid the irritation of oral ketoprofen in gastrointestinal tract,the ketoprofen gel was prepared. METHOD Ketoprofen was dispersed in gel base material after it had been dissolved in alcohol and had been neutralized with triethanolamine.And the method of determination,the irritation experiment and the research of absorption in vitro were studied. RESULTS The prescription of ketoprofen gel was rational.The preparation had low irritation and had high effect on percutaneous absorption in vitro. CONCLUSION The preparation could substitute for oral ketoprofen,and the clinic result should be more observed.
1999, (5): 298-299.
Abstract:
OBJECTIVE To investigate the drug-releasing regularity in vitro of variable concentration mitoxantrone,which wax in a matoxantrone hydroxylapatite ceramic composite encapsulated with wax (DHAQ-PHA-WAX) and DHAQ-PHA without the wax.hydroxylapatite ceramic was used as drug carrier and wax as inhibitor. METHODS The released drug concentration per-day was determined by visible spectrometry at λ =660nm. RESULTS There was a significant difference (P<0.05) between DHAQ-PHA dissolution velocity and DHAQ-PHA-WAX. CONCLUTION Releasing of DHAQ could be controlled with DHAQ-PHA-WAX.
OBJECTIVE To investigate the drug-releasing regularity in vitro of variable concentration mitoxantrone,which wax in a matoxantrone hydroxylapatite ceramic composite encapsulated with wax (DHAQ-PHA-WAX) and DHAQ-PHA without the wax.hydroxylapatite ceramic was used as drug carrier and wax as inhibitor. METHODS The released drug concentration per-day was determined by visible spectrometry at λ =660nm. RESULTS There was a significant difference (P<0.05) between DHAQ-PHA dissolution velocity and DHAQ-PHA-WAX. CONCLUTION Releasing of DHAQ could be controlled with DHAQ-PHA-WAX.
1999, (5): 300-301.
Abstract:
OBJECTIVE To build up a quantitative determination method of shuanghuanglian oral solution. METHODS Thin layer chromatography-scanning was used. RESULTS Good linearity,precision and recovery is obtained. CONCLUSION The method can be successfully employed to determine baicalin and chlorogenic acid in the shuanghuanglian oral solution.
OBJECTIVE To build up a quantitative determination method of shuanghuanglian oral solution. METHODS Thin layer chromatography-scanning was used. RESULTS Good linearity,precision and recovery is obtained. CONCLUSION The method can be successfully employed to determine baicalin and chlorogenic acid in the shuanghuanglian oral solution.
1999, (5): 304-305.
Abstract:
OBJECTIVE To build up a quantitative determination method of shuanghuanglian oral solution. METHODS Thin layer chromatography-scanning was used. RESULTS Good linearity,precision and recovery is obtained. CONCLUSION The method can be successfully employed to determine baicalin and chlorogenic acid in the shuanghuanglian oral solution.
OBJECTIVE To build up a quantitative determination method of shuanghuanglian oral solution. METHODS Thin layer chromatography-scanning was used. RESULTS Good linearity,precision and recovery is obtained. CONCLUSION The method can be successfully employed to determine baicalin and chlorogenic acid in the shuanghuanglian oral solution.
1999, (5): 306-307.
Abstract:
OBJECTIVE To determine the content of total polysaccharides in rhizome,root and leaf of Anemarrhena asphodeloides Bunge. METHODS colorimetry was used. CONCLUSION The content of total polysaccharides in rhizome is the highest,and varies greatly in samples (rhizome)which are collected from different districts but in the same developing stage.
OBJECTIVE To determine the content of total polysaccharides in rhizome,root and leaf of Anemarrhena asphodeloides Bunge. METHODS colorimetry was used. CONCLUSION The content of total polysaccharides in rhizome is the highest,and varies greatly in samples (rhizome)which are collected from different districts but in the same developing stage.
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