Comparison of two kinds of manufacturing technology on compound Fructus crataegi granule
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摘要: 目的 建立复方山楂颗粒的最佳制备工艺。 方法 以产量、颗粒性状、溶化性以及含量为指标,考察槽式混合摇摆制粒与喷雾制粒方法对生产工艺影响。 结果 采用喷雾制粒方式对实际生产中的产量、颗粒性状、溶化性更符合实际要求。结果:采用喷雾制粒工艺后,产量达到130 kg,颗粒呈孔状,大小均匀,外形圆整,流动性好,表明喷雾制粒相对于摇摆制粒更适合制剂生产。 结论 喷雾制粒从各因素考察优越于摇摆制粒。Abstract: Objective To establish the best manufacturing technology of compound Fructus crataegi granule. Method The craft of manufacturing between swing prilling and atomizing prilling was studied. The output , properties, solution in water and total flavonoids were taken as test index. Result The output reached 130 kg, the granule was hole shape, uniformly sized and good fluidity after adopting the atomizing prilling. Conclusion The atomizing prilling was better than swing prilling in manufacturing.
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Key words:
- swing prilling /
- atomizing prilling /
- output /
- properties /
- solute
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