Pharmaceutical care and literature review of type Ⅱ thrombocytopenia induced by anticoagulant therapy on a patient with acute pulmonary embolism
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摘要: 目的 探讨低分子肝素诱导的Ⅱ型血小板减少症（HIT）患者的药学服务要点，从而为临床药师参与此类患者的临床治疗提供参考。 方法 临床药师对1例急性肺栓塞使用低分子肝素钠抗凝治疗导致Ⅱ型血小板减少症的患者进行用药分析及药学监护。检索近年来国内外的相关文献，并结合本病例进行相关性评价，帮助临床医生制订治疗方案。 结果 急性肺栓塞患者治疗安全有效，血小板计数等指标恢复正常。 结论 临床药师应用循证医学证据，充分发挥药学专业特长，积极参与临床Ⅱ型HIT患者的治疗监护，提高药物治疗的安全有效性。
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关键词:
- 急性肺栓塞 /
- 肝素诱导的血小板减少症 /
- 临床药师 /
- 药学监护
Abstract: Objective To explore the key points of pharmaceutical care in patients with thrombocytopenia (HIT) induced by low molecular weight heparin,and to provide reference for clinical pharmacists to participate in the clinical treatment of such patients. Methods Pharmaceutical care was carried out by clinical pharmacists for a patient diagnosed with acute pulmonary embolism who developed progressive thrombocytopenia in the treatment of low molecular weight heparin.To assist clinicians to develop treatment options,literatures published in domestic and international were reviewed and the ADRs relevance of this example were evaluated. Results Pharmaceutical care was applied to the acute pulmonary embolism patient and his platelet count returned to normal eventually. Conclusion Clinical pharmacists should give full play to the expertise of pharmacy specialty,actively participate in the treatment and monitoring of clinical HIT patients,and improve the safety and efficacy of drug therapy. -
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