头孢唑啉钠与氨茶碱、三氮唑核苷在5%葡萄糖注射液中的配伍实验
Compatbility of cefazolin with aminophylline and ribavirin injection solution in 5% glucose injection solution
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摘要: 目的 研究头孢唑啉钠与氨茶碱、三氮唑核苷在5%葡萄糖注射液中的配伍变化,供临床应用参考。方法 配伍实验采用紫外分光光度法和HPLC色谱法进行。结果 头孢唑啉钠与氨茶碱配伍溶液色泽加深,含量略有下降,其余各组色泽未变,含量略有下降。结论 头孢唑啉钠与氨茶碱不能联合应用;头孢唑啉钠与三氨唑核苷可联合应用,但最好在6h用完。
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关键词:
- cefazolin /
- aminophylline /
- ribavirin
Abstract: OBJECTIVE To study the stability of cefazolin with aminophlline and ribavirin in 5% glucose injection solution.METHODS UV spectrophotometric and HPLC was used.RESULTS The content of solution of cefazolin and aminophylline was lower.CONCLUSION Cefazolin shoud not be compatible with aminophylline,and idealy used in 6 hours when compatible with ribavirin.
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